The most important secret behind Corona virus tests, their effectiveness and types.

The latest updates regarding Coronavirus.

So far, pharmaceutical companies have offered more than 300 tests to detect the emerging coronavirus "SARS Cove 2" that causes Covid-19 disease in the human body, but all of them can be divided into 3 types, so what are they? How does it work?

To control the new Coronavirus infections, many tests have been promoted since its introduction at the end of last year until today, and about 350 species are currently used in all laboratories of the world, according to a report published by the Deutsche Welle website, and it can be divided into 3 sections:
  1.     Polymerase chain reaction (PCR) test.

  2.     Antigen-Tests.

  3.     ELISA (enzyme-linked immunosorbent assay).

PCR test:-

One of the most common tests currently used, and it is the examination approved in the first place by the World Health Organization, as well as China, the cradle of the epidemic.

This examination measures the "polymethyl chain reaction" in the human body, and has a long history of detecting several viruses, whether they are related to influenza, acquired human immunodeficiency syndrome (AIDS), or enteroviruses, and viruses associated with the respiratory system, including viruses from Corona platoon.

In this examination, samples of saliva from the throat, or a sample from a lung abscess are taken, and the second step is to determine whether the extracted sample contains the genetic code for SARS-Covid-2 (the genome of the virus), and before that all the genetic information in the sample is isolated, to obtain On pure material that is mixed with the emerging coronavirus itself.

Through a chemical process, it is monitored whether the virus genome is present in the sample taken or not, and if it is discovered, this means that the person is infected with the emerging coronavirus.

The chief expert of the new Coronavirus in Germany, Christian Drosten, likened this matter to the fisherman who throws his net on the seabed, and if he takes it out while it is empty, this does not mean that the sea is free of fish.

Antigen-Tests:-

This examination was developed last summer, and the developed companies took the initiative to introduce types for home use, such as a pregnancy test that can be purchased from a pharmacy, but the home tests did not show the effectiveness promised by the producing companies, as these tests need a connected device that is only available in laboratories.

In this examination, a sample of saliva was used, and one of its advantages is that it is the fastest ever because it provides a result in 15 minutes, but it is also not as accurate as a PCR examination. However, many doctors are betting on this type of examination because of its speed, because it reveals People with a high viral load quickly, which contributes to confining infection.

Immunoassay for the associated enzyme "ELISA":-

This test also called the enzyme immunoassay, is the most accurate, but the most expensive one.

This test detects the presence of antibodies against HIV in the blood serum and is usually used to detect HIV infections (AIDS), and blood samples are taken, and in a complex scientific way the amount of antibodies in the blood is calculated, then the level of immunity Acquired against viral diseases, including the emerging coronavirus.

This particular examination classifies the ability of former patients to donate blood plasma to treat the seriously ill. Copies of this examination have been developed for use in the doctors ’office, but their use remains limited due to their high cost.

When is one of the three tests most appropriate?

The "PCR" test and the antibody test are of great importance in determining the level of the viral load and the duration of infection, and thus determining the period of necessary health isolation. As for the "ELISA" examination, experts need to know the extent of immune strength that people have acquired after being infected with the infection, as it is an indicator It is important to determine the extent to which the foci have reached the stage of "herd immunity", as it is a measure that politicians rely on in developing the necessary measures to deal with the crisis.

Many German universities are currently conducting different studies depending on the "ELISA" examination, specifically on dozens of people who were randomly selected, to detect a viral infection that may not be known until the moment, as a possible result after infection with the emerging coronavirus.